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Motif signatures in stretch enhancers are enriched for disease-associated genetic variants
BACKGROUND: Stretch enhancers (SEs) are large chromatin-defined regulatory elements that are at least 3,000 base pairs (bps) long, in contrast to the median enhancer length of 800 bps. SEs tend to be cell-type specific, regulate cell-type specific gene expression, and are enriched in disease-associa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502539/ https://www.ncbi.nlm.nih.gov/pubmed/26180553 http://dx.doi.org/10.1186/s13072-015-0015-7 |