β-Lapachone suppresses neuroinflammation by modulating the expression of cytokines and matrix metalloproteinases in activated microglia

BACKGROUND: β-Lapachone (β-LAP) is a natural naphthoquinone compound isolated from the lapacho tree (Tabebuia sp.), and it has been used for treatment of rheumatoid arthritis, infection, and cancer. In the present study, we investigated whether β-LAP has anti-inflammatory effects under in vitro and...

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Detalles Bibliográficos
Autores principales: Lee, Eun-Jung, Ko, Hyun-Myung, Jeong, Yeon-Hui, Park, Eun-Mi, Kim, Hee-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502557/
https://www.ncbi.nlm.nih.gov/pubmed/26173397
http://dx.doi.org/10.1186/s12974-015-0355-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502557/
https://www.ncbi.nlm.nih.gov/pubmed/26173397
http://dx.doi.org/10.1186/s12974-015-0355-z

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