ARG2 impairs endothelial autophagy through regulation of MTOR and PRKAA/AMPK signaling in advanced atherosclerosis

Impaired autophagy function and enhanced ARG2 (arginase 2)-MTOR (mechanistic target of rapamycin) crosstalk are implicated in vascular aging and atherosclerosis. We are interested in the role of ARG2 and the potential underlying mechanism(s) in modulation of endothelial autophagy. Using human nonsen...

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Detalles Bibliográficos
Autores principales: Xiong, Yuyan, Yepuri, Gautham, Forbiteh, Michael, Yu, Yi, Montani, Jean-Pierre, Yang, Zhihong, Ming, Xiu-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Basic Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502672/
https://www.ncbi.nlm.nih.gov/pubmed/25484082
http://dx.doi.org/10.4161/15548627.2014.981789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502672/
https://www.ncbi.nlm.nih.gov/pubmed/25484082
http://dx.doi.org/10.4161/15548627.2014.981789

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