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Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury

Dysregulation of autophagy contributes to neuronal cell death in several neurodegenerative and lysosomal storage diseases. Markers of autophagy are also increased after traumatic brain injury (TBI), but its mechanisms and function are not known. Following controlled cortical impact (CCI) brain injur...

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Detalles Bibliográficos
Autores principales: Sarkar, Chinmoy, Zhao, Zaorui, Aungst, Stephanie, Sabirzhanov, Boris, Faden, Alan I, Lipinski, Marta M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502690/
https://www.ncbi.nlm.nih.gov/pubmed/25484084
http://dx.doi.org/10.4161/15548627.2014.981787