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RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy

Macroautophagy is a degradative pathway that sequesters and transports cytosolic cargo in autophagosomes to lysosomes, and its deterioration affects intracellular proteostasis. Membrane dynamics accompanying autophagy are mostly elusive and depend on trafficking processes. RAB GTPase activating prot...

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Detalles Bibliográficos
Autores principales: Spang, Natalie, Feldmann, Anne, Huesmann, Heike, Bekbulat, Fazilet, Schmitt, Verena, Hiebel, Christof, Koziollek-Drechsler, Ingrid, Clement, Albrecht M, Moosmann, Bernd, Jung, Jennifer, Behrends, Christian, Dikic, Ivan, Kern, Andreas, Behl, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502700/
https://www.ncbi.nlm.nih.gov/pubmed/25495476
http://dx.doi.org/10.4161/15548627.2014.994359