Cargando…
RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy
Macroautophagy is a degradative pathway that sequesters and transports cytosolic cargo in autophagosomes to lysosomes, and its deterioration affects intracellular proteostasis. Membrane dynamics accompanying autophagy are mostly elusive and depend on trafficking processes. RAB GTPase activating prot...
Autores principales: | Spang, Natalie, Feldmann, Anne, Huesmann, Heike, Bekbulat, Fazilet, Schmitt, Verena, Hiebel, Christof, Koziollek-Drechsler, Ingrid, Clement, Albrecht M, Moosmann, Bernd, Jung, Jennifer, Behrends, Christian, Dikic, Ivan, Kern, Andreas, Behl, Christian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502700/ https://www.ncbi.nlm.nih.gov/pubmed/25495476 http://dx.doi.org/10.4161/15548627.2014.994359 |
Ejemplares similares
-
The integration of autophagy and cellular trafficking pathways via RAB GAPs
por: Kern, Andreas, et al.
Publicado: (2015) -
The TBC/RabGAP Armus Coordinates Rac1 and Rab7 Functions during Autophagy
por: Carroll, Bernadette, et al.
Publicado: (2013) -
Vps34 and the Armus/TBC-2 Rab GAPs: Putting the brakes on the endosomal Rab5 and Rab7 GTPases
por: Law, Fiona, et al.
Publicado: (2017) -
FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25
por: Rasnitsyn, Alexandra, et al.
Publicado: (2017) -
Novel Modulators of Proteostasis: RNAi Screen of Chromosome I in a Heat Stress Paradigm in C. elegans
por: Kern, Andreas, et al.
Publicado: (2018)