Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions

Endoplasmic reticulum (ER) stress-induced cell death is normally associated with activation of the mitochondrial apoptotic pathway, which is characterized by CYCS (cytochrome c, somatic) release, apoptosome formation, and caspase activation, resulting in cell death. In this study, we demonstrate tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Deegan, Shane, Saveljeva, Svetlana, Logue, Susan E, Pakos-Zebrucka, Karolina, Gupta, Sanjeev, Vandenabeele, Peter, Bertrand, Mathieu JM, Samali, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Basic Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502706/
https://www.ncbi.nlm.nih.gov/pubmed/25470234
http://dx.doi.org/10.4161/15548627.2014.981790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502706/
https://www.ncbi.nlm.nih.gov/pubmed/25470234
http://dx.doi.org/10.4161/15548627.2014.981790

Ejemplares similares