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Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy

The nucleotide-binding domain, leucine-rich repeat containing family caspase recruitment domain containing 4 (NLRC4) inflammasome can be activated by pathogenic bacteria via products translocated through the microbial type III secretion apparatus (T3SS). Recent work has shown that activation of the...

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Detalles Bibliográficos
Autores principales: Jabir, Majid Sakhi, Hopkins, Lee, Ritchie, Neil D., Ullah, Ihsan, Bayes, Hannah K., Li, Dong, Tourlomousis, Panagiotis, Lupton, Alison, Puleston, Daniel, Simon, Anna Katharina, Bryant, Clare, Evans, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502769/
https://www.ncbi.nlm.nih.gov/pubmed/25700738
http://dx.doi.org/10.4161/15548627.2014.981915