Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity

Earlier studies reported allelic deletion of the essential autophagy regulator BECN1 in breast cancers implicating BECN1 loss, and likely defective autophagy, in tumorigenesis. Recent studies have questioned the tumor suppressive role of autophagy, as autophagy-related gene (Atg) defects generally s...

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Detalles Bibliográficos
Autores principales: Cicchini, Michelle, Chakrabarti, Rumela, Kongara, Sameera, Price, Sandy, Nahar, Ritu, Lozy, Fred, Zhong, Hua, Vazquez, Alexei, Kang, Yibin, Karantza, Vassiliki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Translational Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502817/
https://www.ncbi.nlm.nih.gov/pubmed/25483966
http://dx.doi.org/10.4161/auto.34398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502817/
https://www.ncbi.nlm.nih.gov/pubmed/25483966
http://dx.doi.org/10.4161/auto.34398

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