A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90

P2RX7 is an ATP-gated ion channel, which can also exhibit an open state with a considerably wider permeation. However, the functional significance of the movement of molecules through the large pore (LP) and the intracellular signaling events involved are not known. Here, analyzing the consequences...

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Detalles Bibliográficos
Autores principales: Young, Christopher NJ, Sinadinos, Anthony, Lefebvre, Alexis, Chan, Philippe, Arkle, Stephen, Vaudry, David, Gorecki, Dariusz C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Basic Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502824/
https://www.ncbi.nlm.nih.gov/pubmed/25700737
http://dx.doi.org/10.4161/15548627.2014.994402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502824/
https://www.ncbi.nlm.nih.gov/pubmed/25700737
http://dx.doi.org/10.4161/15548627.2014.994402

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