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A comparative study of the localization and membrane topology of members of the RIFIN, STEVOR and PfMC-2TM protein families in Plasmodium falciparum-infected erythrocytes

BACKGROUND: Variant surface antigens (VSA) exposed on the membrane of Plasmodium falciparum infected erythrocytes mediate immune evasion and are important pathogenicity factors in malaria disease. In addition to the well-studied PfEMP1, the small VSA families RIFIN, STEVOR and PfMC-2TM are assumed t...

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Detalles Bibliográficos
Autores principales: Bachmann, Anna, Scholz, Judith Anna Marie, Janßen, Marthe, Klinkert, Mo-Quen, Tannich, Egbert, Bruchhaus, Iris, Petter, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502930/
https://www.ncbi.nlm.nih.gov/pubmed/26173856
http://dx.doi.org/10.1186/s12936-015-0784-2