Comparing genotoxic signatures in cord blood cells from neonates exposed in utero to zidovudine or tenofovir

OBJECTIVES: Zidovudine and tenofovir are the two main nucleos(t)ide analogs used to prevent mother-to-child transmission of HIV. In vitro, both drugs bind to and integrate into human DNA and inhibit telomerase. The objective of the present study was to assess the genotoxic effects of either zidovudi...

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Detalles Bibliográficos
Autores principales: Vivanti, Alexandre, Soheili, Tayebeh S., Cuccuini, Wendy, Luce, Sonia, Mandelbrot, Laurent, Lechenadec, Jerome, Cordier, Anne-Gael, Azria, Elie, Soulier, Jean, Cavazzana, Marina, Blanche, Stéphane, André-Schmutz, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Basic Science: Concise Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502990/
https://www.ncbi.nlm.nih.gov/pubmed/25513819
http://dx.doi.org/10.1097/QAD.0000000000000564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502990/
https://www.ncbi.nlm.nih.gov/pubmed/25513819
http://dx.doi.org/10.1097/QAD.0000000000000564

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