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Joint haplotype assembly and genotype calling via sequential Monte Carlo algorithm
BACKGROUND: Genetic variations predispose individuals to hereditary diseases, play important role in the development of complex diseases, and impact drug metabolism. The full information about the DNA variations in the genome of an individual is given by haplotypes, the ordered lists of single nucle...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503296/ https://www.ncbi.nlm.nih.gov/pubmed/26178880 http://dx.doi.org/10.1186/s12859-015-0651-8 |