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Functional roles of DExD/H-box RNA helicases in Pre-mRNA splicing

Splicing of precursor mRNA takes place via two consecutive steps of transesterification catalyzed by a large ribonucleoprotein complex called the spliceosome. The spliceosome is assembled through ordered binding to the pre-mRNA of five small nuclear RNAs and numerous protein factors, and is disassem...

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Detalles Bibliográficos
Autores principales: Liu, Yen-Chi, Cheng, Soo-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503299/
https://www.ncbi.nlm.nih.gov/pubmed/26173448
http://dx.doi.org/10.1186/s12929-015-0161-z