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Functional roles of DExD/H-box RNA helicases in Pre-mRNA splicing
Splicing of precursor mRNA takes place via two consecutive steps of transesterification catalyzed by a large ribonucleoprotein complex called the spliceosome. The spliceosome is assembled through ordered binding to the pre-mRNA of five small nuclear RNAs and numerous protein factors, and is disassem...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503299/ https://www.ncbi.nlm.nih.gov/pubmed/26173448 http://dx.doi.org/10.1186/s12929-015-0161-z |