Two routes to senescence revealed by real-time analysis of telomerase-negative single lineages

In eukaryotes, telomeres cap chromosome ends to maintain genomic stability. Failure to maintain telomeres leads to their progressive erosion and eventually triggers replicative senescence, a pathway that protects against unrestricted cell proliferation. However, the mechanisms underlying the variabi...

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Detalles Bibliográficos
Autores principales: Xu, Zhou, Fallet, Emilie, Paoletti, Camille, Fehrmann, Steffen, Charvin, Gilles, Teixeira, Maria Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503340/
https://www.ncbi.nlm.nih.gov/pubmed/26158780
http://dx.doi.org/10.1038/ncomms8680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503340/
https://www.ncbi.nlm.nih.gov/pubmed/26158780
http://dx.doi.org/10.1038/ncomms8680

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