Development of a Fluorescent Quenching Based High Throughput Assay to Screen for Calcineurin Inhibitors

Currently there is no effective treatment available for major neurodegenerative disorders associated to protein misfolding, including Alzheimer’s and Parkinson's disease. One of most promising therapeutic approaches under development focuses on inhibiting the misfolding and aggregation pathway....

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Detalles Bibliográficos
Autores principales: Mukherjee, Abhisek, Syeb, Kathleen, Concannon, John, Callegari, Keri, Soto, Claudio, Glicksman, Marcie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503349/
https://www.ncbi.nlm.nih.gov/pubmed/26176772
http://dx.doi.org/10.1371/journal.pone.0131297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503349/
https://www.ncbi.nlm.nih.gov/pubmed/26176772
http://dx.doi.org/10.1371/journal.pone.0131297

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