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Development of a Fluorescent Quenching Based High Throughput Assay to Screen for Calcineurin Inhibitors
Currently there is no effective treatment available for major neurodegenerative disorders associated to protein misfolding, including Alzheimer’s and Parkinson's disease. One of most promising therapeutic approaches under development focuses on inhibiting the misfolding and aggregation pathway....
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503349/ https://www.ncbi.nlm.nih.gov/pubmed/26176772 http://dx.doi.org/10.1371/journal.pone.0131297 |