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Self-organizing human cardiac microchambers mediated by geometric confinement

Tissue morphogenesis and organ formation are the consequences of biochemical and biophysical cues that lead to cellular spatial patterning in development. To model such events in vitro, we use PEG-patterned substrates to geometrically confine human pluripotent stem cell colonies and spatially presen...

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Detalles Bibliográficos
Autores principales: Ma, Zhen, Wang, Jason, Loskill, Peter, Huebsch, Nathaniel, Koo, Sangmo, Svedlund, Felicia L., Marks, Natalie C., Hua, Ethan W., Grigoropoulos, Costas P., Conklin, Bruce R., Healy, Kevin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503387/
https://www.ncbi.nlm.nih.gov/pubmed/26172574
http://dx.doi.org/10.1038/ncomms8413