Cargando…
Self-organizing human cardiac microchambers mediated by geometric confinement
Tissue morphogenesis and organ formation are the consequences of biochemical and biophysical cues that lead to cellular spatial patterning in development. To model such events in vitro, we use PEG-patterned substrates to geometrically confine human pluripotent stem cell colonies and spatially presen...
Autores principales: | Ma, Zhen, Wang, Jason, Loskill, Peter, Huebsch, Nathaniel, Koo, Sangmo, Svedlund, Felicia L., Marks, Natalie C., Hua, Ethan W., Grigoropoulos, Costas P., Conklin, Bruce R., Healy, Kevin E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503387/ https://www.ncbi.nlm.nih.gov/pubmed/26172574 http://dx.doi.org/10.1038/ncomms8413 |
Ejemplares similares
-
Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload
por: Ma, Zhen, et al.
Publicado: (2018) -
Directing cell migration and organization via nanocrater-patterned cell-repellent interfaces
por: Jeon, Hojeong, et al.
Publicado: (2015) -
Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications
por: Mathur, Anurag, et al.
Publicado: (2015) -
Focusing of mammalian cells under an ultrahigh pH gradient created by unidirectional electropulsation in a confined microchamber
por: Loufakis, Despina Nelie, et al.
Publicado: (2014) -
Stability of beating frequency in cardiac myocytes by their community effect measured by agarose microchamber chip
por: Kojima, Kensuke, et al.
Publicado: (2005)