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Gene Transcriptional and Metabolic Profile Changes in Mimetic Aging Mice Induced by D-Galactose
D-galactose injection has been shown to induce many changes in mice that represent accelerated aging. This mouse model has been widely used for pharmacological studies of anti-aging agents. The underlying mechanism of D-galactose induced aging remains unclear, however, it appears to relate to glucos...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503422/ https://www.ncbi.nlm.nih.gov/pubmed/26176541 http://dx.doi.org/10.1371/journal.pone.0132088 |