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Sirtuin Inhibition Adversely Affects Porcine Oocyte Meiosis

Sirtuins have been implicated in diverse biological processes, including oxidative stress, energy metabolism, cell migration, and aging. Here, we employed Sirtuin inhibitors, nicotinamide (NAM) and Sirtinol, to investigate their effects on porcine oocyte maturation respectively. The rate of polar bo...

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Detalles Bibliográficos
Autores principales: Zhang, Liang, Ma, Rujun, Hu, Jin, Ding, Xiaolin, Xu, Yinxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503529/
https://www.ncbi.nlm.nih.gov/pubmed/26176547
http://dx.doi.org/10.1371/journal.pone.0132941