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Synergistic Effects between mTOR Complex 1/2 and Glycolysis Inhibitors in Non-Small-Cell Lung Carcinoma Cells

Cancer metabolism has greatly interested researchers. Mammalian target of rapamycin (mTOR) is dysregulated in a variety of cancers and considered to be an appealing therapeutic target. It has been proven that growth factor signal, mediated by mTOR complex 1 (mTORC1), drives cancer metabolism by regu...

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Detalles Bibliográficos
Autores principales: Jiang, Suhua, Zou, Zhengzhi, Nie, Peipei, Wen, Ruiling, Xiao, Yingying, Tang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503566/
https://www.ncbi.nlm.nih.gov/pubmed/26176608
http://dx.doi.org/10.1371/journal.pone.0132880