Effect of Advanced Glycation End Products on Human Thyroglobulin's Antigenicity as Identified by the Use of Sera from Patients with Hashimoto's Thyroiditis and Gestational Diabetes Mellitus

Advanced glycation end products (AGEs) are formed on proteins after exposure to high concentrations of glucose and modify protein's immunogenicity. Herein, we investigated whether the modification of thyroglobulin (Tg) by AGEs influences its antigenicity and immunogenicity. Human Tg was incubat...

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Detalles Bibliográficos
Autores principales: Hatzioannou, A., Kanistras, I., Mantzou, E., Anastasiou, E., Peppa, M., Sarantopoulou, V., Lymberi, P., Alevizaki, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503572/
https://www.ncbi.nlm.nih.gov/pubmed/26229534
http://dx.doi.org/10.1155/2015/849615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503572/
https://www.ncbi.nlm.nih.gov/pubmed/26229534
http://dx.doi.org/10.1155/2015/849615

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