RLN2 Is a Positive Regulator of AKT-2-Induced Gene Expression Required for Osteosarcoma Cells Invasion and Chemoresistance

The aim of the study was to determine the effect of H2 relaxin (RLN2) on invasion, migration, and chemosensitivity to cisplatin in human osteosarcoma U2-OS and MG-63 cells and then to investigate the effect of RLN2 on the AKT/NF-κB signaling pathway. The expression of RLN2, p-AKT (Ser473), and p-ERK...

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Detalles Bibliográficos
Autores principales: Ma, Jinfeng, Huang, Hai, Han, Zenggang, Zhu, Changzheng, Yue, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503584/
https://www.ncbi.nlm.nih.gov/pubmed/26229955
http://dx.doi.org/10.1155/2015/147468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503584/
https://www.ncbi.nlm.nih.gov/pubmed/26229955
http://dx.doi.org/10.1155/2015/147468

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