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Complementation of the Yeast Model System Reveals that Caenorhabditis elegans OCT-1 Is a Functional Transporter of Anthracyclines

The yeast plasma membrane protein Agp2 belongs to the family of amino acid transporters. It acts as a regulator that controls the expression of several uptake transporter genes such as DUR3 and SAM3 encoding two high-affinity polyamine permeases. agp2Δ mutants display extreme resistance to several c...

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Detalles Bibliográficos
Autores principales: Brosseau, Nicolas, Andreev, Emil, Ramotar, Dindial
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503637/
https://www.ncbi.nlm.nih.gov/pubmed/26177450
http://dx.doi.org/10.1371/journal.pone.0133182