The SMC Loader Scc2 Promotes ncRNA Biogenesis and Translational Fidelity

The Scc2-Scc4 complex is essential for loading the cohesin complex onto DNA. Cohesin has important roles in chromosome segregation, DSB repair, and chromosome condensation. Here we report that Scc2 is important for gene expression in budding yeast. Scc2 and the transcriptional regulator Paf1 collabo...

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Detalles Bibliográficos
Autores principales: Zakari, Musinu, Trimble Ross, Rhonda, Peak, Allison, Blanchette, Marco, Seidel, Chris, Gerton, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503661/
https://www.ncbi.nlm.nih.gov/pubmed/26176819
http://dx.doi.org/10.1371/journal.pgen.1005308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503661/
https://www.ncbi.nlm.nih.gov/pubmed/26176819
http://dx.doi.org/10.1371/journal.pgen.1005308

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