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The SMC Loader Scc2 Promotes ncRNA Biogenesis and Translational Fidelity
The Scc2-Scc4 complex is essential for loading the cohesin complex onto DNA. Cohesin has important roles in chromosome segregation, DSB repair, and chromosome condensation. Here we report that Scc2 is important for gene expression in budding yeast. Scc2 and the transcriptional regulator Paf1 collabo...
Autores principales: | Zakari, Musinu, Trimble Ross, Rhonda, Peak, Allison, Blanchette, Marco, Seidel, Chris, Gerton, Jennifer L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503661/ https://www.ncbi.nlm.nih.gov/pubmed/26176819 http://dx.doi.org/10.1371/journal.pgen.1005308 |
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