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High Genotypic Discordance of Concurrent Mycobacterium tuberculosis Isolates from Sputum and Blood of HIV-Infected Individuals

BACKGROUND: Among HIV-infected individuals with CD4 less than 200 cells/mm(3), tuberculosis often has an atypical presentation, is more likely to be disseminated and is diagnostically challenging. We sought to understand the genotypic discordance of concurrent sputum and blood M. tuberculosis (MTB)...

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Detalles Bibliográficos
Autores principales: Ssengooba, Willy, Cobelens, Frank G., Nakiyingi, Lydia, Mboowa, Gerald, Armstrong, Derek T., Manabe, Yukari C., Joloba, Moses L., de Jong, Bouke C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503667/
https://www.ncbi.nlm.nih.gov/pubmed/26176604
http://dx.doi.org/10.1371/journal.pone.0132581