Cargando…

High Genotypic Discordance of Concurrent Mycobacterium tuberculosis Isolates from Sputum and Blood of HIV-Infected Individuals

BACKGROUND: Among HIV-infected individuals with CD4 less than 200 cells/mm(3), tuberculosis often has an atypical presentation, is more likely to be disseminated and is diagnostically challenging. We sought to understand the genotypic discordance of concurrent sputum and blood M. tuberculosis (MTB)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ssengooba, Willy, Cobelens, Frank G., Nakiyingi, Lydia, Mboowa, Gerald, Armstrong, Derek T., Manabe, Yukari C., Joloba, Moses L., de Jong, Bouke C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503667/ https://www.ncbi.nlm.nih.gov/pubmed/26176604 http://dx.doi.org/10.1371/journal.pone.0132581

Ejemplares similares

Whole genome sequencing reveals mycobacterial microevolution among concurrent isolates from sputum and blood in HIV infected TB patients
por: Ssengooba, Willy, et al.
Publicado: (2016)

Clinical Utility of a Novel Molecular Assay in Various Combination Strategies with Existing Methods for Diagnosis of HIV-Related Tuberculosis in Uganda
por: Ssengooba, Willy, et al.
Publicado: (2014)

Performance of loop-mediated isothermal amplification assay in the diagnosis of pulmonary tuberculosis in a high prevalence TB/HIV rural setting in Uganda
por: Nakiyingi, Lydia, et al.
Publicado: (2018)

Chest X-ray interpretation does not complement Xpert MTB/RIF in diagnosis of smear-negative pulmonary tuberculosis among TB-HIV co-infected adults in a resource-limited setting
por: Nakiyingi, Lydia, et al.
Publicado: (2021)

Effect of mixed Mycobacterium tuberculosis infection on rapid molecular diagnostics among patients starting MDR-TB treatment in Uganda
por: Komakech, Kevin, et al.
Publicado: (2023)

Predictors and outcomes of mycobacteremia among HIV-infected smear- negative presumptive tuberculosis patients in Uganda
por: Nakiyingi, Lydia, et al.
Publicado: (2015)

Sputum microbiota profiles of treatment-naïve TB patients in Uganda before and during first-line therapy
por: Kateete, David Patrick, et al.
Publicado: (2021)

Rifampicin resistance mutations in the 81 bp RRDR of rpoB gene in Mycobacterium tuberculosis clinical isolates using Xpert(®)MTB/RIF in Kampala, Uganda: a retrospective study
por: Mboowa, Gerald, et al.
Publicado: (2014)

Rifampicin susceptibility discordance between Xpert MTB/RIF G4 and Xpert Ultra before MDRT-TB treatment initiation: A case report from Uganda
por: Ssengooba, Willy, et al.
Publicado: (2021)

Clinico-pathological features of tuberculosis due to Mycobacterium tuberculosis Uganda genotype in patients with tuberculous lymphadenitis: a cross sectional study
por: Wamala, Dan, et al.
Publicado: (2014)

Cough Aerosol Cultures of Mycobacterium tuberculosis: Insights on TST / IGRA Discordance and Transmission Dynamics
por: Jones-López, Edward C., et al.
Publicado: (2015)

Incremental Yield of Serial Sputum Cultures for Diagnosis of Tuberculosis among HIV Infected Smear Negative Pulmonary TB Suspects in Kampala, Uganda
por: Ssengooba, Willy, et al.
Publicado: (2012)

Whole genome sequencing to complement tuberculosis drug resistance surveys in Uganda
por: Ssengooba, Willy, et al.
Publicado: (2016)

Predictors for MTB Culture-Positivity among HIV-Infected Smear-Negative Presumptive Tuberculosis Patients in Uganda: Application of New Tuberculosis Diagnostic Technology
por: Nakiyingi, Lydia, et al.
Publicado: (2015)

Agreement of Middle brook 7H10 with Lowenstein Jensen and accuracy of the Sensititre MYCOTB plate using either method as a reference standard for Mycobacterium tuberculosis first line drug susceptibility testing
por: Ssengooba, Willy, et al.
Publicado: (2018)

Species and genotypic diversity of non-tuberculous mycobacteria isolated from children investigated for pulmonary tuberculosis in rural Uganda
por: Asiimwe, Benon B, et al.
Publicado: (2013)

Feasibility of establishing a biosafety level 3 tuberculosis culture laboratory of acceptable quality standards in a resource-limited setting: an experience from Uganda
por: Ssengooba, Willy, et al.
Publicado: (2015)

An Early Morning Sputum Sample Is Necessary for the Diagnosis of Pulmonary Tuberculosis, Even with More Sensitive Techniques: A Prospective Cohort Study among Adolescent TB-Suspects in Uganda
por: Ssengooba, Willy, et al.
Publicado: (2012)

High prevalence of phenotypic pyrazinamide resistance and its association with pncA gene mutations in Mycobacterium tuberculosis isolates from Uganda
por: Naluyange, Resty, et al.
Publicado: (2020)

Tuberculosis risk factors among tuberculosis patients in Kampala, Uganda: implications for tuberculosis control
por: Kirenga, Bruce J, et al.
Publicado: (2015)

Feasibility of magnetic bead technology for concentration of mycobacteria in sputum prior to fluorescence microscopy
por: Albert, Heidi, et al.
Publicado: (2011)

Multicenter Study of the Accuracy of the BD MAX Multidrug-resistant Tuberculosis Assay for Detection of Mycobacterium tuberculosis Complex and Mutations Associated With Resistance to Rifampin and Isoniazid
por: Shah, Maunank, et al.
Publicado: (2020)

Clinical Predictors and Accuracy of Empiric Tuberculosis Treatment among Sputum Smear-Negative HIV-Infected Adult TB Suspects in Uganda
por: Nakiyingi, Lydia, et al.
Publicado: (2013)

Variation and risk factors of drug resistant tuberculosis in sub-Saharan Africa: a systematic review and meta-analysis
por: Lukoye, Deus, et al.
Publicado: (2015)

Assessing a transmission network of Mycobacterium tuberculosis in an African city using single nucleotide polymorphism threshold analysis
por: Yassine, Edriss, et al.
Publicado: (2021)

Genotypic characterization directly applied to sputum improves the detection of Mycobacterium africanum West African 1, under-represented in positive cultures
por: Sanoussi, C. N’Dira, et al.
Publicado: (2017)

Evaluation of Cepheid's Xpert MTB/RIF Test on Pleural Fluid in the Diagnosis of Pleural Tuberculosis in a High Prevalence HIV/TB Setting
por: Lusiba, John K., et al.
Publicado: (2014)

Point-of-Care Lateral Flow Assays for Tuberculosis and Cryptococcal Antigenuria Predict Death in HIV Infected Adults in Uganda
por: Manabe, Yukari C., et al.
Publicado: (2014)

Discordance of the Repeat GeneXpert MTB/RIF Test for Rifampicin Resistance Detection Among Patients Initiating MDR-TB Treatment in Uganda
por: Ssengooba, Willy, et al.
Publicado: (2021)

Baseline Xpert MTB/RIF ct values predict sputum conversion during the intensive phase of anti-TB treatment in HIV infected patients in Kampala, Uganda: a retrospective study
por: Namugenyi, Juliet, et al.
Publicado: (2021)

Evaluation of Xpert(®) MTB/XDR test for susceptibility testing of Mycobacterium tuberculosis to first and second-line drugs in Uganda
por: Katamba, Achilles, et al.
Publicado: (2023)

Evaluation of Xpert MTB/XDR test for susceptibility testing of Mycobacterium tuberculosis to first and second-line drugs in Uganda
por: Katamba, Achilles, et al.
Publicado: (2023)

Variable ability of rapid tests to detect Mycobacterium tuberculosis rpoB mutations conferring phenotypically occult rifampicin resistance
por: Torrea, Gabriela, et al.
Publicado: (2019)

Accuracy of different Xpert MTB/Rif implementation strategies in programmatic settings at the regional referral hospitals in Uganda: Evidence for country wide roll out
por: Muttamba, Winters, et al.
Publicado: (2018)

Predominance of Uganda genotype of Mycobacterium tuberculosis isolated from Ugandan patients with tuberculous lymphadenitis
por: Wamala, Dan, et al.
Publicado: (2015)

Mycobacterium tuberculosis disease associates with higher HIV-1-specific antibody responses
por: Adeoye, Bukola, et al.
Publicado: (2023)

Recurrent pneumothorax in a human immunodeficiency virus-positive patient with multidrug-resistant tuberculosis: a rare case of bronchopleural fistula: a case report
por: Nakiyingi, Lydia, et al.
Publicado: (2022)

Health seeking behavior among individuals presenting with chronic cough at referral hospitals in Uganda; Missed opportunity for early tuberculosis diagnosis
por: Muttamba, Winters, et al.
Publicado: (2019)

Do Xpert MTB/RIF Cycle Threshold Values Provide Information about Patient Delays for Tuberculosis Diagnosis?
por: Ssengooba, Willy, et al.
Publicado: (2016)

Discordance in Mycobacterium tuberculosis Rifampin Susceptibility
por: Kalokhe, Ameeta S., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_q9j6pqpmotrsmv7kd0l24hfpki