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miR-34 and p53: New Insights into a Complex Functional Relationship

miR-34, a tumor suppressor miRNA family transcriptionally activated by p53, is considered a critical mediator of p53 function. However, knockout of the mouse miR-34 family has little or no effect on the p53 response. The relative contribution of different miR-34 family members to p53 function or how...

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Detalles Bibliográficos
Autores principales: Navarro, Francisco, Lieberman, Judy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503669/
https://www.ncbi.nlm.nih.gov/pubmed/26177460
http://dx.doi.org/10.1371/journal.pone.0132767