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The Human Autoantibody Response to Apolipoprotein A-I Is Focused on the C-Terminal Helix: A New Rationale for Diagnosis and Treatment of Cardiovascular Disease?

BACKGROUND: Cardiovascular disease (CVD) is the leading cause of death worldwide and new approaches for both diagnosis and treatment are required. Autoantibodies directed against apolipoprotein A-I (ApoA-I) represent promising biomarkers for use in risk stratification of CVD and may also play a dire...

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Detalles Bibliográficos
Autores principales: Pagano, Sabrina, Gaertner, Hubert, Cerini, Fabrice, Mannic, Tiphaine, Satta, Nathalie, Teixeira, Priscila Camillo, Cutler, Paul, Mach, François, Vuilleumier, Nicolas, Hartley, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503694/
https://www.ncbi.nlm.nih.gov/pubmed/26177543
http://dx.doi.org/10.1371/journal.pone.0132780