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IL28B genotype predicts response to chronic hepatitis C triple therapy with telaprevir or boceprevir in treatment naïve and treatment-experienced patients other than prior partial- and null-responders

Single nucleotide polymorphisms (SNPs) in the IL28B gene were shown to have limited utility in predicting response to telaprevir and boceprevir in treatment of chronic HCV infection in clinical trials. Data outside of the clinical trial setting are lacking. We assessed the value of single and combin...

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Detalles Bibliográficos
Autores principales: Calisti, Giorgio, Tavares, Amanda, Macartney, Malcolm J, McCormick, Adele, Labbett, Wendy, Jacobs, Michael, Dusheiko, Geoffrey, Rosenberg, William M, Haque, Tanzina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503705/
https://www.ncbi.nlm.nih.gov/pubmed/26191484
http://dx.doi.org/10.1186/s40064-015-1137-x