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Evaluating the Stability of RNA-Seq Transcriptome Profiles and Drug-Induced Immune-Related Expression Changes in Whole Blood

Methods were developed to evaluate the stability of rat whole blood expression obtained from RNA sequencing (RNA-seq) and assess changes in whole blood transcriptome profiles in experiments replicated over time. Expression was measured in globin-depleted RNA extracted from the whole blood of Sprague...

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Detalles Bibliográficos
Autores principales: Bowyer, John F., Tranter, Karen M., Hanig, Joseph P., Crabtree, Nathaniel M., Schleimer, Robert P., George, Nysia I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503719/
https://www.ncbi.nlm.nih.gov/pubmed/26177368
http://dx.doi.org/10.1371/journal.pone.0133315