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Isolation and Characterization of a Monobody with a Fibronectin Domain III Scaffold That Specifically Binds EphA2
Monobodies are binding scaffold proteins originating from a human fibronectin domain III (Fn3) scaffold that can be easily engineered with specificity and affinity. Human EphA2 (hEphA2) is an early detection marker protein for various tumors including lung, breast, and colon cancer. In this study, w...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503726/ https://www.ncbi.nlm.nih.gov/pubmed/26177208 http://dx.doi.org/10.1371/journal.pone.0132976 |