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Isolation and Characterization of a Monobody with a Fibronectin Domain III Scaffold That Specifically Binds EphA2

Monobodies are binding scaffold proteins originating from a human fibronectin domain III (Fn3) scaffold that can be easily engineered with specificity and affinity. Human EphA2 (hEphA2) is an early detection marker protein for various tumors including lung, breast, and colon cancer. In this study, w...

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Detalles Bibliográficos
Autores principales:	Park, Seung-Hwan, Park, Sukho, Kim, Dong-Yeon, Pyo, Ayoung, Kimura, Richard H., Sathirachinda, Ataya, Choy, Hyon E., Min, Jung-Joon, Gambhir, Sanjiv Sam, Hong, Yeongjin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503726/ https://www.ncbi.nlm.nih.gov/pubmed/26177208 http://dx.doi.org/10.1371/journal.pone.0132976

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