The Gcn2 Regulator Yih1 Interacts with the Cyclin Dependent Kinase Cdc28 and Promotes Cell Cycle Progression through G2/M in Budding Yeast

The Saccharomyces cerevisiae protein Yih1, when overexpressed, inhibits the eIF2 alpha kinase Gcn2 by competing for Gcn1 binding. However, deletion of YIH1 has no detectable effect on Gcn2 activity, suggesting that Yih1 is not a general inhibitor of Gcn2, and has no phenotypic defect identified so f...

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Detalles Bibliográficos
Autores principales: Silva, Richard C., Dautel, Martina, Di Genova, Bruno M., Amberg, David C., Castilho, Beatriz A., Sattlegger, Evelyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503747/
https://www.ncbi.nlm.nih.gov/pubmed/26176233
http://dx.doi.org/10.1371/journal.pone.0131070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503747/
https://www.ncbi.nlm.nih.gov/pubmed/26176233
http://dx.doi.org/10.1371/journal.pone.0131070

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