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Small ncRNA Expression-Profiling of Blood from Hemophilia A Patients Identifies miR-1246 as a Potential Regulator of Factor 8 Gene

Hemophilia A (HA) is a bleeding disorder caused by deficiency of functional plasma clotting factor VIII (FVIII). Genetic mutations in the gene encoding FVIII (F8) have been extensively studied. Over a thousand different mutations have been reported in the F8 gene. These span a diverse range of mutat...

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Detalles Bibliográficos
Autores principales: Sarachana, Tewarit, Dahiya, Neetu, Simhadri, Vijaya L., Pandey, Gouri Shankar, Saini, Surbhi, Guelcher, Christine, Guerrera, Michael F., Kimchi-Sarfaty, Chava, Sauna, Zuben E., Atreya, Chintamani D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503767/
https://www.ncbi.nlm.nih.gov/pubmed/26176629
http://dx.doi.org/10.1371/journal.pone.0132433