Pro-Inflammatory Cytokine IL-1β Up-Regulates CXC Chemokine Receptor 4 via Notch and ERK Signaling Pathways in Tongue Squamous Cell Carcinoma

Chronic inflammation contributes to tumor development through the induction of oncogenic mutations, genomic instability, early tumor promotion, and enhanced angiogenesis. Here, we report that IL-1 receptor 1 (IL-1R1) was expressed in 40 of 41 human tongue squamous cell carcinomas (TSCC). IL-1β up-re...

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Detalles Bibliográficos
Autores principales: Sun, Yi, Zhu, Demao, Wang, Guihua, Wang, Di, Zhou, Huashan, Liu, Xueting, Jiang, Manli, Liao, Lingjuan, Zhou, Zhiguang, Hu, Jinyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503771/
https://www.ncbi.nlm.nih.gov/pubmed/26176534
http://dx.doi.org/10.1371/journal.pone.0132677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503771/
https://www.ncbi.nlm.nih.gov/pubmed/26176534
http://dx.doi.org/10.1371/journal.pone.0132677

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