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swDMR: A Sliding Window Approach to Identify Differentially Methylated Regions Based on Whole Genome Bisulfite Sequencing

DNA methylation is a widespread epigenetic modification that plays an essential role in gene expression through transcriptional regulation and chromatin remodeling. The emergence of whole genome bisulfite sequencing (WGBS) represents an important milestone in the detection of DNA methylation. Charac...

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Detalles Bibliográficos
Autores principales: Wang, Zhen, Li, Xianfeng, Jiang, Yi, Shao, Qianzhi, Liu, Qi, Chen, BingYu, Huang, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503785/
https://www.ncbi.nlm.nih.gov/pubmed/26176536
http://dx.doi.org/10.1371/journal.pone.0132866