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Genetic stability of pneumococcal isolates during 35 days of human experimental carriage

BACKGROUND: Pneumococcal carriage is a reservoir for transmission and a precursor to pneumococcal disease. The experimental human pneumococcal carriage model provides a useful tool to aid vaccine licensure through the measurement of vaccine efficacy against carriage (VEcol). Documentation of the gen...

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Detalles Bibliográficos
Autores principales: Gladstone, R.A., Gritzfeld, J.F., Coupland, P., Gordon, S.B., Bentley, S.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503797/
https://www.ncbi.nlm.nih.gov/pubmed/26006086
http://dx.doi.org/10.1016/j.vaccine.2015.05.021