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Microglia recapitulate a hematopoietic master regulator network in the aging human frontal cortex
Microglia form the immune system of the brain. Previous studies in cell cultures and animal models suggest altered activation states and cellular senescence in the aged brain. Instead, we analyzed 3 transcriptome data sets from the postmortem frontal cortex of 381 control individuals to show that mi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503803/ https://www.ncbi.nlm.nih.gov/pubmed/26002684 http://dx.doi.org/10.1016/j.neurobiolaging.2015.04.008 |