Current and future implications of basic and translational research on amyloid-β peptide production and removal pathways

Inherited variants in multiple different genes are associated with increased risk for Alzheimer's disease (AD). In many of these genes, the inherited variants alter some aspect of the production or clearance of the neurotoxic amyloid β-peptide (Aβ). Thus missense, splice site or duplication mut...

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Detalles Bibliográficos
Autores principales: Bohm, C., Chen, F., Sevalle, J., Qamar, S., Dodd, R., Li, Y., Schmitt-Ulms, G., Fraser, P.E., St George-Hyslop, P.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503820/
https://www.ncbi.nlm.nih.gov/pubmed/25748120
http://dx.doi.org/10.1016/j.mcn.2015.02.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503820/
https://www.ncbi.nlm.nih.gov/pubmed/25748120
http://dx.doi.org/10.1016/j.mcn.2015.02.016

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