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Generation of Rat Embryonic Germ Cells via Inhibition of TGFß and MEK Pathways

OBJECTIVE: Embryonic germ (EG) cells are the results of reprogramming primordial germ cells (PGC) in vitro. Studying these cells can be of benefit in determining the mechanism by which specialized cells acquire pluripotency. Therefore in the current study we have tried to derive rat EG cells with in...

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Detalles Bibliográficos
Autores principales: Mohammadi, Alireza, Attari, Farnoosh, Babapour, Vahab, Hassani, Seyedeh-Nafiseh, Masoudi, Najmehsadat, Shahverdi, Abdolhossein, Baharvand, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503842/
https://www.ncbi.nlm.nih.gov/pubmed/26199907