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N-Acetyl Cysteine Inhibits Endothelin-1-Induced ROS Dependent Cardiac Hypertrophy through Superoxide Dismutase Regulation

OBJECTIVE: Oxidative stress down regulates antioxidant enzymes including superoxide dismutase (SOD) and contributes to the development of cardiac hypertrophy. N-Acetyl cysteine (NAC) can enhance the SOD activity, so the aim of this study is to highlight the inhibitory role of NAC against endothelin-...

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Detalles Bibliográficos
Autores principales: Mushtaq, Sobia, Ali, Tahir, Javed, Qamar, Tabassum, Sobia, Murtaza, Iram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503849/
https://www.ncbi.nlm.nih.gov/pubmed/26199914