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Nebulised amphotericin B-polymethacrylic acid nanoparticle prophylaxis prevents invasive aspergillosis

Aspergillus species are the major life threatening fungal pathogens in transplant patients. Germination of inhaled fungal spores initiates infection, causes severe pneumonia, and has a mortality of > 50%. This is leading to the consideration of pre-exposure prophylaxis to prevent infection. We ma...

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Detalles Bibliográficos
Autores principales: Shirkhani, Khojasteh, Teo, Ian, Armstrong-James, Darius, Shaunak, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503863/
https://www.ncbi.nlm.nih.gov/pubmed/25791815
http://dx.doi.org/10.1016/j.nano.2015.02.012