Dysregulation of locus coeruleus development in congenital central hypoventilation syndrome

Human congenital central hypoventilation syndrome (CCHS), resulting from mutations in transcription factor PHOX2B, manifests with impaired responses to hypoxemia and hypercapnia especially during sleep. To identify brainstem structures developmentally affected in CCHS, we analyzed two postmortem neo...

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Detalles Bibliográficos
Autores principales: Nobuta, Hiroko, Cilio, Maria Roberta, Danhaive, Olivier, Tsai, Hui-Hsin, Tupal, Srinivasan, Chang, Sandra M., Murnen, Alice, Kreitzer, Faith, Bravo, Verenice, Czeisler, Catherine, Gokozan, Hamza Numan, Gygli, Patrick, Bush, Sean, Weese-Mayer, Debra E., Conklin, Bruce, Yee, Siu-Pok, Huang, Eric J., Gray, Paul A., Rowitch, David, Otero, José Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503865/
https://www.ncbi.nlm.nih.gov/pubmed/25975378
http://dx.doi.org/10.1007/s00401-015-1441-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503865/
https://www.ncbi.nlm.nih.gov/pubmed/25975378
http://dx.doi.org/10.1007/s00401-015-1441-0

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