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Cell type-specific Nrf2 expression in multiple sclerosis lesions

Oxidative injury appears to play a major role in the propagation of demyelination and neurodegeneration in multiple sclerosis (MS). It has been suggested that endogenous anti-oxidant defense mechanisms within MS lesions are insufficient to prevent spreading of damage. Thus, current therapeutic appro...

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Detalles Bibliográficos
Autores principales: Licht-Mayer, Simon, Wimmer, Isabella, Traffehn, Sarah, Metz, Imke, Brück, Wolfgang, Bauer, Jan, Bradl, Monika, Lassmann, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503875/
https://www.ncbi.nlm.nih.gov/pubmed/26087903
http://dx.doi.org/10.1007/s00401-015-1452-x