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Reliable LC3 and p62 Autophagy Marker Detection in Formalin Fixed Paraffin Embedded Human Tissue by Immunohistochemistry

Autophagy assures cellular homeostasis, and gains increasing importance in cancer, where it impacts on carcinogenesis, propagation of the malignant phenotype and development of resistance. To date, its tissue-based analysis by immunohistochemistry remains poorly standardized. Here we show the feasib...

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Detalles Bibliográficos
Autores principales: Schläfli, A.M., Berezowska, S., Adams, O., Langer, R., Tschan, M.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503968/
https://www.ncbi.nlm.nih.gov/pubmed/26150155
http://dx.doi.org/10.4081/ejh.2015.2481