Uric Acid Produces an Inflammatory Response through Activation of NF-κB in the Hypothalamus: Implications for the Pathogenesis of Metabolic Disorders

Epidemiological studies have shown that an elevated uric acid (UA) level predicts the development of metabolic syndrome and diabetes; however, there is no direct evidence of this, and the underlying mechanism remains unclear. Here, we showed that a high-UA diet triggered the expression of pro-inflam...

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Detalles Bibliográficos
Autores principales: Lu, Wenjie, Xu, Youzhi, Shao, Xiaoni, Gao, Fabao, Li, Yan, Hu, Jing, Zuo, Zeping, Shao, Xue, Zhou, Liangxue, Zhao, Yinglan, Cen, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503982/
https://www.ncbi.nlm.nih.gov/pubmed/26179594
http://dx.doi.org/10.1038/srep12144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503982/
https://www.ncbi.nlm.nih.gov/pubmed/26179594
http://dx.doi.org/10.1038/srep12144

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